A case series of concomitant treatment of perhexiline with amiodarone

H Gilutz, MP Frenneaux… - Therapeutic drug …, 2012 - journals.lww.com
Background Concomitant treatment with amiodarone and perhsexiline has been considered
to be relatively contraindicated because of the hypothetical risk of potentiated adverse
effects mediated by additive inhibition of carnitine palmitoyl transferase 1. Aim To study the
prevalence of adverse effects associated with the concomitant use of perhexiline and
amiodarone. Methods A retrospective analysis of a single hospital database of patients
receiving perhexiline and amiodarone between July 2009 and April 2011. Files were …
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